Bristol, Tennessee, September 13, 2025
News Summary
USAntibiotics has announced a partnership with Walmart and McKesson to enhance the production and distribution of amoxicillin in the U.S. This collaboration aims to manufacture millions of doses starting in August 2025 from the Bristol, Tennessee facility, which can meet the nation’s entire demand for the antibiotic. The initiative is part of a broader effort to bolster domestic medicine manufacturing and ensure healthcare providers have reliable access to essential medications.
Bristol, Tennessee – USAntibiotics has partnered with Walmart and McKesson in a significant move to enhance the production and distribution of amoxicillin, a widely used antibiotic, within the United States. This collaboration is set to supply millions of doses of amoxicillin to various healthcare providers starting in August 2025.
The initiative aims to expand the U.S.-based production of amoxicillin at USAntibiotics’ 394,000-square-foot facility located in Bristol, Tennessee. This facility possesses the capacity to meet 100% of the nation’s demand for this critical antibiotic. Through the partnership, Walmart pharmacies and McKesson’s vast distribution network will ensure the availability of amoxicillin across the country.
This partnership has been welcomed by local representatives, with U.S. Representative Diana Harshbarger highlighting its importance for both Northeast Tennessee and the broader context of America’s health security. The collaboration is also seen as part of a larger effort to re-establish domestic manufacturing of essential medicines that has been diminishing in recent years.
USAntibiotics President Patrick Cashman remarked on the partnership’s significance, emphasizing its commitment to enhancing America’s health security through reliable antibiotic supply. Walmart has committed to investing $350 billion in U.S.-made products by the year 2030, and the collaboration with USAntibiotics aligns with this goal by supporting local manufacturing.
McKesson, recognized for operating one of the largest pharmaceutical distribution networks in the country, will play a crucial role in making sure these antibiotics reach healthcare providers efficiently. The collaboration is facilitated by ClarusONE Sourcing Services, which is aiding the partnership in various aspects of procurement and distribution.
Background Information
Amoxicillin is a vital antibiotic commonly prescribed for a range of infections, including respiratory tract infections, urinary tract infections, and skin infections. As the only U.S. manufacturer of both amoxicillin and amoxicillin clavulanate, USAntibiotics occupies a unique position in the pharmaceutical landscape. The need for reliable domestic sources of essential drugs has gained attention, particularly during health crises such as the COVID-19 pandemic, which highlighted vulnerabilities in global supply chains.
The commitment from major companies like Walmart and McKesson to bolster domestic manufacturing capacity is seen as a proactive approach to ensuring accessible and locally-produced medications. This strategy not only addresses immediate healthcare needs but also aims to secure the U.S. against future supply chain disruptions.
Strategic Importance of the Partnership
The partnership between USAntibiotics, Walmart, and McKesson encompasses several strategic benefits:
- Increased Production: The collaboration significantly boosts the domestic production of essential antibiotics.
- Healthcare Strengthening: Ensures that healthcare providers have continuous access to necessary medications.
- Investment in Local Economy: Aligns with Walmart’s initiative to invest in American-made products, fostering local job creation and economic growth.
With the backing of these significant players in the retail and healthcare sectors, USAntibiotics is poised to make a substantial impact on the availability of amoxicillin and contribute to the health security of the nation.
FAQs
What is the purpose of the partnership between USAntibiotics, Walmart, and McKesson?
The partnership aims to expand the production and distribution of amoxicillin in the U.S., ensuring that millions of doses will be available to healthcare providers starting in August 2025.
Where will the amoxicillin be manufactured?
Amoxicillin will be manufactured at USAntibiotics’ facility located in Bristol, Tennessee, which has the capacity to fulfill the entire national demand for this antibiotic.
What impact does this partnership have on healthcare in the U.S.?
The partnership improves access to domestically produced medicines, enhances healthcare security, and contributes to the efforts to re-establish U.S. manufacturing of essential drugs.
Key Features of the Partnership
| Feature | Details |
|---|---|
| Manufacturing Location | Bristol, Tennessee |
| Production Capacity | 100% of U.S. demand for amoxicillin |
| Start Date | August 2025 |
| Distribution Partners | Walmart and McKesson |
| Investment by Walmart | $350 billion in U.S.-made products by 2030 |
Deeper Dive: News & Info About This Topic
HERE Resources
Additional Resources
- Fox Business
- Wikipedia: Amoxicillin
- Chain Store Age
- Google Search: USAntibiotics partnership Walmart
- Fortune Business Insights
- Google Scholar: antibiotics market analysis
- Herald Courier
- Encyclopedia Britannica: antibiotics manufacturing
- Pharma Times
- Google News: nasal sprays antibiotic use

Author: STAFF HERE BRISTOL WRITTER
The BRISTOL STAFF WRITER represents the experienced team at HEREBristol.com, your go-to source for actionable local news and information in Bristol, Sullivan County, and beyond. Specializing in "news you can use," we cover essential topics like product reviews for personal and business needs, local business directories, politics, real estate trends, neighborhood insights, and state news affecting the area—with deep expertise drawn from years of dedicated reporting and strong community input, including local press releases and business updates. We deliver top reporting on high-value events such as the Bristol Rhythm & Roots Reunion, NASCAR races at Bristol Motor Speedway, Border Bash concert series, and the Hot Bristol Night Car Show. Our coverage extends to key organizations like the Bristol Chamber of Commerce, Believe in Bristol, and the Birthplace of Country Music, plus leading businesses in healthcare, manufacturing, and entertainment that power the local economy such as Ballad Health, Strongwell, and Bristol Motor Speedway. As part of the broader HERE network, including HEREChattanooga.com, HEREKnoxville.com, HEREMemphis.com, and HERENashville.com, we provide comprehensive, credible insights into Tennessee's dynamic landscape.


